BEFORE AND AFTER
COSMELAN Treatment Results
Cosmelan® Depigmentation treatment is intended to dramatically reduce the
appearance of pigmentation and uneven skin tone resulting from Melasma,
acne scarring and other dermal pigmentation.  Cosmelan® has been
successful in addressing pigmentation previously non-responsive to
treatment.  This treatment has an in-office and an “at home” component.   
Cosmelan® has very high safety margin.
Cosmelan® Depigmentation treatment action mechanism is based on the
inhibition of tyrosinase, a basic enzyme in the melanin formation process.
Several of the substances present in the Cosmelan® formula act by blocking
this enzyme, or even by inverting the metabolic process of the transformation
chain.
ADVANTAGES
The Cosmelan® Depigmentation treatment offers a series of major
advantages and benefits compared with other types of depigmentation
products found in the market:
•        Very effective in all types of melasma
•        Rapid and easy depigmenting action
•        Compatible with ALL skin types (Fitzpatrick I – VI)
•        Light peeling effect
•        Rejuvenates the skin
•        Treatment can be used all year round
•        Beneficial for acne patients
•        Does not contain TCA
•        High safety margin

RESULTS
Clinical studies conducted by the manufacturers show that: “In 99% of the
cases, the clearance of the blemishes improves by 95%...”

ONE WEEK after starting the Cosmelan® Depigmentation treatment, a
noticeable significant improvement of the skin is observed! The reduction of
the treated blemish is detected and the appearance of new luminous and
rejuvenated skin is present.
At the end of the Cosmelan® Depigmentation treatment, the blemishes start to
disappear altogether, so that, although the you may be able to “locate” the
place where the spot was, the pigmentation is significantly reduced and
nobody will be able to see it just by looking at it.

PRELIMINARY INFORMATION FOR THE PATIENT
The Cosmelan® Depigmentation treatment initiated at the medical office must
be continued at home, on a daily basis, according to the guidelines indicated.
The treatment must not be interrupted under any circumstances, during the
whole time prescribed.
It is completely forbidden to combine the Cosmelan® Depigmentation
treatment with other depigmentation treatments, as the appearance of
undesired effects cannot be guaranteed.
Treatment control visits are recommended. 8 days after beginning of
treatment, 15 days after, and a follow up visit every month thereafter.

TREATMENT APPLICATION - Cosmelan® Depigmentation treatment
Cosmelan® is a mask applied at the dermatology office and remains on your
face 4 to 10 hours depending on the indication.  The mask is washed off at
home and you may expect three to five days of light to heavy peeling, redness
and sensitivity.  After the third or fourth day, the skin appears healthy and
luminous and the marks begin to fade.

HOME TREATMENT - Cosmelan® 2 Maintenance Cream
The second phase of the Cosmelan® treatment consist of a home
maintenance cream Cosmelan 2® with the intention of securing the
depigmentation by association of agents such as Kojic Acid, Phytic Acid, and
Vitamin C. We have added a physical agent to block the sun and guarantee
that the UV rays do not keep on aggravating unwanted cutaneous hyper
pigmentation.  Cosmelan 2® cream should be applied 2 times per day during
the first two weeks, and once a day from the third week on for several months
depending on the indication as directed by the physician to achieve an
optimum depigmentation response.

We often reserve some Cosmelan® 1 Mask for a “touch-up” application if
necessary in one month.  This helps achieve excellent results on even the
most stubborn areas.   
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PIGMENTATION
Gene Rubinstein, M.D.
Dermatologist, Certified by the American Board of Dermatology
Studio City, CA
(818) 505-9300
Pigmentation
BEFORE AND AFTER
Obagi Treatment Results
The Obagi Nu-Derm System, a physician-prescribed skin care system,
accelerates the cellular turnover. This System penetrates below the skin's
surface to correct damage in all layers of the skin (the stratum corneum, the
epidermis and the dermis). It corrects functions of the skin at the cellular level,
to Transform skin's cellular function to help it look and act younger and
healthier. The System triggers a Therapeutic Cascade™ that:


- Pushes fresher cells to the surface faster, for smoother skin, reduced
wrinkles and increased tolerance  

- Corrects current pigmentation (freckles and age spots) and prevents the
appearance of new pigmentation  

- Promotes more uniform cells at the deepest layer for better skin structure
and balanced, even skin tone  

- Increases collagen and elastin for firmer, more resilient skin  

- Increases nutrient's natural hydration and circulation for supple, healthy-
looking skin  



"I am so glad I decided to try the Obagi
system. It was one of the best decisions
I made in my life.  Thank you for helping
me re-gain my confidence."
         T.P., Studio City, CA, 2006
Uneven Texture and Skin Tone
Rejuvenation
Acne Scarring
CALL TODAY TO SCHEDULE AN APPOINTMENT

Gene Rubinstein, M.D.
Dermatologist and Laser Specialist

(818) 505-9300
OBAGI Skin Renewal System
Pigmentation
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